Research & Development
Investigational Therapeutic for Episodic Cardiovascular Conditions
We are studying our lead investigational candidate, etripamil, for the acute treatment of patients with paroxysmal supraventricular tachycardia (PSVT) and atrial fibrillation with rapid ventricular rate (AFib-RVR), wherever their episodes may occur.
To ensure the safety of trial participants, new processes have been put in place to reduce the risks associated with the COVID-19 pandemic. These potential changes include, but are not limited to, the use of tele-medicine to conduct study visit procedures, conduct of study procedures outside of the clinical site (i.e., at a patient’s home) by site personnel or by trained but non-site personnel, and the distribution of investigational products by alternative secure delivery methods
Clinical trials are a critical part of the drug development process designed to assess an investigational agent’s safety and effectiveness in treating a disease, adding to the scientific body of knowledge on diseases and how they may be treated.
For information regarding access to Milestone’s clinical trials, please visit clinicaltrials.gov.
Phase 3 Clinical Program
Milestone’s pivotal Phase 3 program of etripamil in PSVT, which was designed in consultation with U.S. and European Union regulatory authorities, consists of three distinct trials evaluating the safety and efficacy of etripamil in at-home settings and without the need for medical supervision.
Phase 2 Clinical Program
Milestone has an ongoing Phase 2 clinical trial for patients experiencing atrial fibrillation with a rapid ventricular rate (AFib-RVR).